Version 5.4
Homo sapiens Gene: SERGEF
Summary
InnateDB Gene IDBG-34368.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERGEF
Gene Name secretion regulating guanine nucleotide exchange factor
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000129158
Encoded Proteins
IDBP-34370
secretion regulating guanine nucleotide exchange factor
IDBP-601501
secretion regulating guanine nucleotide exchange factor
IDBP-588151
secretion regulating guanine nucleotide exchange factor
IDBP-590600
secretion regulating guanine nucleotide exchange factor
IDBP-596520
secretion regulating guanine nucleotide exchange factor
IDBP-599468
secretion regulating guanine nucleotide exchange factor
IDBP-595362
secretion regulating guanine nucleotide exchange factor
IDBP-593691
secretion regulating guanine nucleotide exchange factor
IDBP-591804
secretion regulating guanine nucleotide exchange factor
IDBP-602517
secretion regulating guanine nucleotide exchange factor
IDBP-601808
secretion regulating guanine nucleotide exchange factor
IDBP-593610
secretion regulating guanine nucleotide exchange factor
IDBP-596509
secretion regulating guanine nucleotide exchange factor
IDBP-590826
secretion regulating guanine nucleotide exchange factor
IDBP-583732
secretion regulating guanine nucleotide exchange factor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:17788048-18013162
Strand Reverse strand
Band p15.1
Transcripts
ENST00000265965 ENSP00000265965
ENST00000531299
ENST00000531926
ENST00000528369
ENST00000527494 ENSP00000431490
ENST00000525422 ENSP00000434330
ENST00000528200 ENSP00000434188
ENST00000524589
ENST00000529440
ENST00000529151 ENSP00000436111
ENST00000532546 ENSP00000432763
ENST00000525920 ENSP00000436648
ENST00000532265 ENSP00000431314
ENST00000533241 ENSP00000435003
ENST00000525168
ENST00000529728 ENSP00000437297
ENST00000530613 ENSP00000436080
ENST00000532389 ENSP00000435898
ENST00000530925 ENSP00000433870
ENST00000533328 ENSP00000433383
ENST00000532212
ENST00000524716 ENSP00000433884
ENST00000530951
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005087 Ran guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0032853 positive regulation of Ran GTPase activity
GO:0050709 negative regulation of protein secretion
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0045111 intermediate filament cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030839
View Gene Order
ENSBTAG00000005340
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.32470
RefSeq NM_012139
HUGO
OMIM
CCDS CCDS7828
HPRD 06926
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca