Version 5.4
Homo sapiens Gene: KRT72
Summary
InnateDB Gene IDBG-34803.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRT72
Gene Name keratin 72
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000170486
Encoded Proteins
IDBP-34767
keratin 72
IDBP-34805
keratin 72
IDBP-604057
keratin 72
IDBP-593604
keratin 72
IDBP-586412
keratin 72
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:52585589-52601538
Strand Reverse strand
Band q13.13
Transcripts
ENST00000354310 ENSP00000346269
ENST00000293745 ENSP00000293745
ENST00000537672 ENSP00000441160
ENST00000550829 ENSP00000446881
ENST00000549979 ENSP00000449324
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005198 structural molecule activity
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005882 intermediate filament
GO:0045095 keratin filament
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000056605
View Gene Order
ENSBTAG00000007904
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.662013
RefSeq NM_001146225 NM_001146226 NM_080747
HUGO
OMIM
CCDS CCDS53795 CCDS8833
HPRD 09746
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca