Version 5.4
Homo sapiens Gene: BEAN1
Summary
InnateDB Gene IDBG-34927.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BEAN1
Gene Name brain expressed, associated with NEDD4, 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000166546
Encoded Proteins
IDBP-34929
brain expressed, associated with NEDD4, 1
IDBP-585926
brain expressed, associated with NEDD4, 1
IDBP-748679
IDBP-745743
IDBP-751686
IDBP-753068
IDBP-810541
brain expressed, associated with NEDD4, 1
IDBP-810545
brain expressed, associated with NEDD4, 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:66427297-66493529
Strand Forward strand
Band q21
Transcripts
ENST00000299694 ENSP00000299694
ENST00000536005 ENSP00000442793
ENST00000561796 ENSP00000455212
ENST00000562146 ENSP00000462088
ENST00000562849 ENSP00000456822
ENST00000566654
ENST00000563075
ENST00000569272
ENST00000564819 ENSP00000456430
ENST00000618932 ENSP00000477843
ENST00000622872 ENSP00000483700
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0008219 cell death
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031872
View Gene Order
ENSBTAG00000009762
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 146227
UniGene
RefSeq NM_001136106 NM_001178020 NM_001197224 NM_001197225
HUGO HGNC:24160
OMIM 612051
CCDS CCDS54015 CCDS58469 CCDS58470
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 146227

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca