Version 5.4
Homo sapiens Gene: MEX3C
Summary
InnateDB Gene IDBG-3505.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MEX3C
Gene Name mex-3 homolog C (C. elegans)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000176624
Encoded Proteins
IDBP-294664
mex-3 homolog C (C. elegans)
IDBP-725746
IDBP-809676
mex-3 RNA binding family member C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of a family of proteins with two K homology (KH) RNA-binding domains and a C-terminal RING-finger domain. The protein interacts with mRNA via the KH domains, and the protein shuttles between the nucleus and cytoplasm. Polymorphisms in this gene may contribute to hypertension. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:51174550-51218304
Strand Reverse strand
Band q21.2
Transcripts
ENST00000406189 ENSP00000385610
ENST00000592416 ENSP00000468078
ENST00000591040
ENST00000616921 ENSP00000482566
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 4 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0003415 chondrocyte hypertrophy
GO:0008152 metabolic process
GO:0045598 regulation of fat cell differentiation
GO:0097009 energy homeostasis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037253
View Gene Order
ENSBTAG00000014886
Not yet available
Cross-References
SwissProt
TrEMBL B2R538 B3KTW5 M9T4I7
UniProt Splice Variant
Entrez Gene 51320
UniGene
RefSeq NM_016626
HUGO HGNC:28040
OMIM 611005
CCDS CCDS11951
HPRD
IMGT
EMBL AK096190 AK312049 KC456343 KC456344
GenPept AGI99528 AGI99529 BAG34985 BAG53227
RNA Seq Atlas 51320

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca