Version 5.4
Homo sapiens Gene: DYNC1LI2
Summary
InnateDB Gene IDBG-35488.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DYNC1LI2
Gene Name dynein, cytoplasmic 1, light intermediate chain 2
Synonyms DNCLI2; LIC2
Species Homo sapiens
Ensembl Gene ENSG00000135720
Encoded Proteins
IDBP-35490
dynein, cytoplasmic 1, light intermediate chain 2
IDBP-378568
dynein, cytoplasmic 1, light intermediate chain 2
IDBP-378574
dynein, cytoplasmic 1, light intermediate chain 2
IDBP-748796
IDBP-754291
IDBP-749039
IDBP-748123
IDBP-751937
IDBP-747771
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Cytoplasmic dynein is a microtubule-associated motor protein (Hughes et al., 1995 [PubMed 7738094]). See DYNC1H1 (MIM 600112) for general information about dyneins.[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:66720893-66751798
Strand Reverse strand
Band q22.1
Transcripts
ENST00000258198 ENSP00000258198
ENST00000443351 ENSP00000394289
ENST00000440564 ENSP00000408566
ENST00000565532
ENST00000561727
ENST00000569320 ENSP00000462017
ENST00000566150 ENSP00000457707
ENST00000567499
ENST00000568180 ENSP00000457464
ENST00000568453
ENST00000563628 ENSP00000462434
ENST00000570201
ENST00000564559 ENSP00000462224
ENST00000564090 ENSP00000463124
ENST00000564833
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
Experimentally validated
Total 30 [view]
Protein-Protein 30 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0006810 transport
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0051642 centrosome localization
Cellular Component
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005868 cytoplasmic dynein complex
GO:0005874 microtubule
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035770
View Gene Order
ENSBTAG00000000458
Not yet available
Pathways
NETPATH
REACTOME
REACT_121399
MHC class II antigen presentation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
KEGG
hsa04962
Vasopressin-regulated water reabsorption pathway
hsa04145
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.369068 Hs.644723
RefSeq NM_001286157 NM_006141
HUGO
OMIM
CCDS CCDS10818 CCDS67049
HPRD 09923
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca