Version 5.4
Homo sapiens Gene: IGFBP6
Summary
InnateDB Gene IDBG-35796.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IGFBP6
Gene Name insulin-like growth factor binding protein 6
Synonyms IBP6
Species Homo sapiens
Ensembl Gene ENSG00000167779
Encoded Proteins
IDBP-35798
insulin-like growth factor binding protein 6
IDBP-594479
insulin-like growth factor binding protein 6
IDBP-602046
insulin-like growth factor binding protein 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:53097436-53102345
Strand Forward strand
Band q13.13
Transcripts
ENST00000301464 ENSP00000301464
ENST00000548547 ENSP00000448953
ENST00000548176 ENSP00000449344
ENST00000549628
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005520 insulin-like growth factor binding
GO:0031994 insulin-like growth factor I binding
Biological Process
GO:0001558 regulation of cell growth
GO:0007165 signal transduction
GO:0008285 negative regulation of cell proliferation
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000023046
View Gene Order
ENSBTAG00000021467
Not yet available
Pathways
NETPATH
REACTOME
REACT_15428
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) pathway
REACT_17015
Metabolism of proteins pathway
KEGG
INOH
INOH website
IGF1 signaling pathway pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_002178
HUGO
OMIM
CCDS CCDS8846
HPRD 00902
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca