Homo sapiens Gene: DEFB125
Summary
InnateDB Gene IDBG-36533.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DEFB125
Gene Name defensin, beta 125
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000178591
Encoded Proteins
defensin, beta 125
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Defensins are cysteine-rich cationic polypeptides that are important in the host immunologic response to invading microorganisms. The protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:87250-97094
Strand Forward strand
Band p13
Transcripts
ENST00000382410 ENSP00000371847
ENST00000608838
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0042742 defense response to bacterium
Cellular Component
GO:0005576 extracellular region
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Beta defensins pathway
Defensins pathway
Innate Immune System pathway
Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_153325
HUGO
OMIM
CCDS CCDS12989
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas