Version 5.4
Homo sapiens Gene: KLHL1
Summary
InnateDB Gene IDBG-37027.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KLHL1
Gene Name kelch-like 1 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000150361
Encoded Proteins
IDBP-37029
kelch-like 1 (Drosophila)
IDBP-592468
kelch-like 1 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The KLHL1 protein belongs to a family of actin-organizing proteins related to Drosophila Kelch (Nemes et al., 2000 [PubMed 10888605]).[supplied by OMIM, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:69700594-70108493
Strand Reverse strand
Band q21.33
Transcripts
ENST00000377844 ENSP00000367075
ENST00000545028 ENSP00000439602
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0007626 locomotory behavior
GO:0007628 adult walking behavior
GO:0016358 dendrite development
GO:0021680 cerebellar Purkinje cell layer development
GO:0030036 actin cytoskeleton organization
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0030425 dendrite
GO:0043025 neuronal cell body
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022076
View Gene Order
ENSBTAG00000008647
Not yet available
Cross-References
SwissProt Q9NR64
TrEMBL F5H1J3 Q96RF4
UniProt Splice Variant
Entrez Gene 57626
UniGene Hs.508201
RefSeq NM_001286725 NM_020866
HUGO HGNC:6352
OMIM 605332
CCDS CCDS73582 CCDS9445
HPRD
IMGT
EMBL AB040923 AF252279 AF252283 AH010896 AK291435 AL160391 AL162378 AL353738 AL356384 AL590554 AL596302 CH471093
GenPept AAF81716 AAF81719 AAK69769 BAA96014 BAF84124 CAH70258 CAH71287 CAH73330 CAH73834 EAW80503
RNA Seq Atlas 57626

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca