InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: RPL29

Summary

InnateDB Gene

IDBG-38122.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPL29

Gene Name

ribosomal protein L29

Synonyms

HIP; HUMRPL29; L29; RPL29_3_370; RPL29P10

Species

Homo sapiens

Ensembl Gene

ENSG00000162244

Encoded Proteins

IDBP-38124

ribosomal protein L29

IDBP-476484

ribosomal protein L29

IDBP-473720

ribosomal protein L29

IDBP-475999

ribosomal protein L29

IDBP-480721

ribosomal protein L29

IDBP-483596

ribosomal protein L29

IDBP-479914

ribosomal protein L29

IDBP-479346

ribosomal protein L29

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L29E family of ribosomal proteins. The protein is also a peripheral membrane protein expressed on the cell surface that directly binds heparin. Although this gene was previously reported to map to 3q29-qter, it is believed that it is located at 3p21.3-p21.2. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:51993600-51995942

Strand

Reverse strand

Band

p21.2

Transcripts

ENST00000294189	ENSP00000294189
ENST00000466397	ENSP00000418868
ENST00000480306	ENSP00000419333
ENST00000479017	ENSP00000418153
ENST00000495383	ENSP00000420673
ENST00000475248	ENSP00000417048
ENST00000492277	ENSP00000418346
ENST00000481629	ENSP00000418839
ENST00000486565

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 58 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	58 [view]
Protein-Protein	58 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0008201	heparin binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0007566	embryo implantation
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0044267	cellular protein metabolic process