Version 5.4
Homo sapiens Gene: SETD7
Summary
InnateDB Gene IDBG-38481.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SETD7
Gene Name SET domain containing (lysine methyltransferase) 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000145391
Encoded Proteins
IDBP-38483
SET domain containing (lysine methyltransferase) 7
IDBP-295322
SET domain containing (lysine methyltransferase) 7
IDBP-295320
SET domain containing (lysine methyltransferase) 7
IDBP-481746
SET domain containing (lysine methyltransferase) 7
IDBP-811702
SET domain containing (lysine methyltransferase) 7
IDBP-811703
SET domain containing (lysine methyltransferase) 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:139495941-139606699
Strand Reverse strand
Band q31.1
Transcripts
ENST00000274031 ENSP00000274031
ENST00000404104 ENSP00000385913
ENST00000406354 ENSP00000384336
ENST00000515101
ENST00000506866 ENSP00000427300
ENST00000608795 ENSP00000476712
ENST00000608958 ENSP00000476302
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 57 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 57 [view]
Protein-Protein 57 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002039 p53 binding
GO:0005515 protein binding
GO:0016279 protein-lysine N-methyltransferase activity
GO:0018024 histone-lysine N-methyltransferase activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0016568 chromatin modification
GO:0018026 peptidyl-lysine monomethylation
GO:0018027 peptidyl-lysine dimethylation
GO:0034968 histone lysine methylation
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037111
View Gene Order
ENSBTAG00000003581
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00310
Lysine degradation pathway
INOH
PID NCI
p53regulationpathway
p53 pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.480792 Hs.595666 Hs.618879 Hs.706992
RefSeq NM_030648
HUGO
OMIM
CCDS CCDS3748
HPRD 16226
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca