Homo sapiens Gene: CSTF3 | |||||||||||||||||||||
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Summary | |||||||||||||||||||||
InnateDB Gene | IDBG-38556.6 | ||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||
Gene Symbol | CSTF3 | ||||||||||||||||||||
Gene Name | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | ||||||||||||||||||||
Synonyms | CSTF-77 | ||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||
Ensembl Gene | ENSG00000176102 | ||||||||||||||||||||
Encoded Proteins |
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
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Protein Structure | |||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
Summary |
The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3\' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||
Genomic Location | Chromosome 11:33077188-33162371 | ||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||
Band | p13 | ||||||||||||||||||||
Transcripts | |||||||||||||||||||||
Interactions | |||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||
NETPATH | |||||||||||||||||||||
REACTOME |
Processing of Intronless Pre-mRNAs pathway
mRNA 3'-end processing pathway
mRNA Splicing - Major Pathway pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
Cleavage of Growing Transcript in the Termination Region pathway
RNA Polymerase II Transcription Termination pathway
RNA Polymerase II Transcription pathway
Processing of Capped Intronless Pre-mRNA pathway
mRNA Splicing pathway
Gene Expression pathway
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KEGG |
mRNA surveillance pathway pathway
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INOH | |||||||||||||||||||||
PID NCI | |||||||||||||||||||||
Cross-References | |||||||||||||||||||||
SwissProt | |||||||||||||||||||||
TrEMBL | |||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
UniGene | Hs.44402 Hs.611525 Hs.626383 | ||||||||||||||||||||
RefSeq | NM_001033505 NM_001033506 NM_001326 | ||||||||||||||||||||
HUGO | |||||||||||||||||||||
OMIM | |||||||||||||||||||||
CCDS | CCDS44563 CCDS44564 CCDS7883 | ||||||||||||||||||||
HPRD | 02651 | ||||||||||||||||||||
IMGT | |||||||||||||||||||||
EMBL | |||||||||||||||||||||
GenPept | |||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||