Version 5.4
Homo sapiens Gene: CADPS2
Summary
InnateDB Gene IDBG-38565.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CADPS2
Gene Name Ca++-dependent secretion activator 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000081803
Encoded Proteins
IDBP-38567
Ca++-dependent secretion activator 2
IDBP-38569
Ca++-dependent secretion activator 2
IDBP-234707
Ca++-dependent secretion activator 2
IDBP-385931
Ca++-dependent secretion activator 2
IDBP-385932
Ca++-dependent secretion activator 2
IDBP-474195
Ca++-dependent secretion activator 2
IDBP-807649
Ca++-dependent secretion activator 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. Mutations in this gene may contribute to autism susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:122318425-122886759
Strand Reverse strand
Band q31.32
Transcripts
ENST00000334010 ENSP00000333940
ENST00000313070 ENSP00000325581
ENST00000397721 ENSP00000380833
ENST00000412584 ENSP00000400401
ENST00000449022 ENSP00000398481
ENST00000462699 ENSP00000419418
ENST00000476131
ENST00000615869 ENSP00000484355
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0046872 metal ion binding
Biological Process
GO:0009267 cellular response to starvation
GO:0015031 protein transport
GO:0016082 synaptic vesicle priming
GO:0045921 positive regulation of exocytosis
Cellular Component
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0030054 cell junction
GO:0030659 cytoplasmic vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0042734 presynaptic membrane
GO:0045211 postsynaptic membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000017978
View Gene Order
ENSBTAG00000005110
Not yet available
Cross-References
SwissProt Q86UW7
TrEMBL B3KNS2 C9IYE1 X5D7B2 X5DNG0
UniProt Splice Variant
Entrez Gene 93664
UniGene Hs.649459 Hs.740589
RefSeq NM_001009571 NM_001167940 NM_017954 XM_005250695 XM_005250696 XM_005250697 XM_005250698 XM_005250699 XM_005250700 XM_005250701 XM_005250702 XM_005250703 XM_005250704 XM_005250705 XM_005250706 XM_005250707 XM_005250708
HUGO HGNC:16018
OMIM 609978
CCDS CCDS47691 CCDS55158
HPRD
IMGT
EMBL AB046811 AC004594 AC004838 AC004986 AC006009 AC006463 AC015983 AC091438 AF401638 AK000768 AK025672 AK054853 AK098170 AL833058 AY264289 BC054339 BC136601 BC144278 CH236947 CH471070 KJ534800 KJ534801 KJ534805
GenPept AAH54339 AAI36602 AAI44279 AAN38707 AAP22132 AHW56440 AHW56441 AHW56445 BAA91372 BAB13417 BAB15210 BAG51434 CAH56288 EAL24339 EAW83572
RNA Seq Atlas 93664

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca