Version 5.4
Homo sapiens Gene: UQCR10
Summary
InnateDB Gene IDBG-3868.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UQCR10
Gene Name ubiquinol-cytochrome c reductase, complex III subunit X
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000184076
Encoded Proteins
IDBP-3870
ubiquinol-cytochrome c reductase, complex III subunit X
IDBP-294624
ubiquinol-cytochrome c reductase, complex III subunit X
IDBP-808921
ubiquinol-cytochrome c reductase, complex III subunit X
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary UCRC is a subunit of mitochondrial complex III (ubiquinol-cytochrome c reductase; EC 1.10.2.2), which forms the middle segment of the respiratory chain of the inner mitochondrial membrane (Schagger et al., 1995 [PubMed 8592474]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:29767369-29770413
Strand Forward strand
Band q12.2
Transcripts
ENST00000330029 ENSP00000332887
ENST00000401406 ENSP00000384962
ENST00000616603 ENSP00000482098
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008121 ubiquinol-cytochrome-c reductase activity
Biological Process
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
GO:0022904 respiratory electron transport chain
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005740 mitochondrial envelope
GO:0005743 mitochondrial inner membrane
GO:0005750 mitochondrial respiratory chain complex III
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000059534
View Gene Order
ENSBTAG00000000913
Not yet available
Pathways
NETPATH
REACTOME
REACT_22393
Respiratory electron transport pathway
REACT_6305
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_111083
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_111217
Metabolism pathway
KEGG
hsa05010
Alzheimer's disease pathway
hsa00190
Oxidative phosphorylation pathway
hsa05012
Parkinson's disease pathway
hsa05016
Huntington's disease pathway
hsa04260
Cardiac muscle contraction pathway
INOH
PID NCI
Cross-References
SwissProt Q9UDW1
TrEMBL
UniProt Splice Variant
Entrez Gene 29796
UniGene
RefSeq NM_001003684 NM_013387
HUGO HGNC:30863
OMIM 610843
CCDS CCDS46681 CCDS46680
HPRD 13691
IMGT
EMBL AB028598 AC004882 AF161468 BC005402 BC015971
GenPept AAF29083 AAH05402 AAH15971 BAB20672
RNA Seq Atlas 29796

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca