Version 5.4
| Homo sapiens Gene: GDF1 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-38953.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | GDF1 | ||||||
| Gene Name | growth differentiation factor 1 | ||||||
| Synonyms | |||||||
| Species | Homo sapiens | ||||||
| Ensembl Gene | ENSG00000130283 | ||||||
| Encoded Proteins |
growth differentiation factor 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a bicistronic mRNA that also encodes the longevity assurance gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 19:18868545-18896096 | ||||||
| Strand | Reverse strand | ||||||
| Band | p13.11 | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||
| NETPATH | |||||||
| REACTOME |
Signaling by NODAL pathway
Developmental Biology pathway
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| KEGG | |||||||
| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | P27539 | ||||||
| TrEMBL | A0A024R7N8 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 2657 | ||||||
| UniGene | |||||||
| RefSeq | |||||||
| HUGO | HGNC:4214 | ||||||
| OMIM | 602880 | ||||||
| CCDS | CCDS42526 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | AC003972 CH471106 M62302 | ||||||
| GenPept | AAA58501 AAB94786 EAW84743 EAW84744 | ||||||
| RNA Seq Atlas | 2657 | ||||||