Version 5.4
Homo sapiens Gene: MARS2
Summary
InnateDB Gene IDBG-405074.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MARS2
Gene Name methionyl-tRNA synthetase 2, mitochondrial
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000247626
Encoded Proteins
IDBP-78051
methionyl-tRNA synthetase 2, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:197705369-197708387
Strand Forward strand
Band q33.1
Transcripts
ENST00000282276 ENSP00000282276
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004825 methionine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006431 methionyl-tRNA aminoacylation
GO:0008219 cell death
GO:0010467 gene expression
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000046994
View Gene Order
ENSBTAG00000002056
Not yet available
Pathways
NETPATH
REACTOME
REACT_15302
Mitochondrial tRNA aminoacylation pathway
REACT_15482
tRNA Aminoacylation pathway
REACT_71
Gene Expression pathway
KEGG
hsa00450
Selenocompound metabolism pathway
hsa00970
Aminoacyl-tRNA biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q96GW9
TrEMBL
UniProt Splice Variant
Entrez Gene 92935
UniGene Hs.116602 Hs.733607
RefSeq NM_138395
HUGO HGNC:25133
OMIM 609728
CCDS CCDS33358
HPRD 14363
IMGT
EMBL AB107013 AC073058 AK098121 BC009115 BC040934 BC126294
GenPept AAH09115 AAH40934 AAI26295 AAX93244 BAC05238 BAC92749
RNA Seq Atlas 92935

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca