Version 5.4
| Homo sapiens Gene: AKAP2 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-405943.4 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | AKAP2 | ||||||||||||||||||
| Gene Name | A kinase (PRKA) anchor protein 2 | ||||||||||||||||||
| Synonyms | AKAP-2; AKAPKL; PRKA2 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000241978 | ||||||||||||||||||
| Encoded Proteins |
A kinase (PRKA) anchor protein 2
A kinase (PRKA) anchor protein 2
A kinase (PRKA) anchor protein 2
A kinase (PRKA) anchor protein 2
A kinase (PRKA) anchor protein 2
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
PALM2-AKAP2 mRNAs are naturally occurring read-through products of the neighboring PALM2 and AKAP2 genes. The significance of these read-through mRNAs and the function the resulting fusion protein products have not yet been determined. Alternative splicing of this gene results in several transcript variants encoding different isoforms, but the full-length nature of some of these variants has not been defined. [provided by RefSeq, Oct 2010] The protein encoded by this gene binds to the regulatory subunit of protein kinase A and is found associated with the actin cytoskeleton. The encoded protein mediates signals carried by cAMP and may be involved in creating polarity in certain signaling processes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] The protein encoded by this gene binds to the regulatory subunit of protein kinase A and is found associated with the actin cytoskeleton. The encoded protein mediates signals carried by cAMP and may be involved in creating polarity in certain signaling processes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 9:110048598-110172512 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | q31.3 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
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Gene ID
Gene Order
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| Cross-References | |||||||||||||||||||
| SwissProt | Q9Y2D5 | ||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 445815 | ||||||||||||||||||
| UniGene | Hs.604711 Hs.733138 | ||||||||||||||||||
| RefSeq | NM_001004065 NM_001136562 NM_001198656 | ||||||||||||||||||
| HUGO | HGNC:372 | ||||||||||||||||||
| OMIM | 604582 | ||||||||||||||||||
| CCDS | CCDS43861 CCDS48003 CCDS56581 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AB023137 AJ303079 AK057098 AK300427 AL110268 AL158823 AL158829 AL353598 AL353806 AL627225 BC140818 BC146863 BC171800 CH471105 | ||||||||||||||||||
| GenPept | AAI40819 AAI46864 AAI71800 BAA76764 BAG51862 BAG62154 CAB53707 CAC38839 CAI10811 CAI12434 CAI13896 CAI39560 CAI40816 EAW59057 | ||||||||||||||||||
| RNA Seq Atlas | 11217 445815 | ||||||||||||||||||