Version 5.4
Homo sapiens Gene: AHCYL2
Summary
InnateDB Gene IDBG-40716.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AHCYL2
Gene Name adenosylhomocysteinase-like 2
Synonyms ADOHCYASE3
Species Homo sapiens
Ensembl Gene ENSG00000158467
Encoded Proteins
IDBP-40718
adenosylhomocysteinase-like 2
IDBP-386211
adenosylhomocysteinase-like 2
IDBP-475134
adenosylhomocysteinase-like 2
IDBP-483886
adenosylhomocysteinase-like 2
IDBP-476746
adenosylhomocysteinase-like 2
IDBP-477979
adenosylhomocysteinase-like 2
IDBP-480887
adenosylhomocysteinase-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene acts as a homotetramer and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:129225023-129430211
Strand Forward strand
Band q32.1
Transcripts
ENST00000325006 ENSP00000315931
ENST00000446544 ENSP00000413639
ENST00000461161
ENST00000460109 ENSP00000419717
ENST00000474594 ENSP00000420459
ENST00000490911 ENSP00000420801
ENST00000466993 ENSP00000419608
ENST00000466924 ENSP00000419346
ENST00000472554
ENST00000491079
ENST00000492628
ENST00000477028
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004013 adenosylhomocysteinase activity
GO:0051287 NAD binding
Biological Process
GO:0006730 one-carbon metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029772
View Gene Order
ENSBTAG00000001754
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00270
Cysteine and methionine metabolism pathway
INOH
INOH website
Methionine Cysteine metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.600789 Hs.614543 Hs.707143
RefSeq NM_001130720 NM_001130722 NM_001130723 NM_015328 XM_005250237
HUGO
OMIM
CCDS CCDS47706 CCDS47707 CCDS47708 CCDS5812
HPRD 11113
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca