Homo sapiens Gene: C2orf15 | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-407719.4 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | C2orf15 | ||||||||||
Gene Name | chromosome 2 open reading frame 15 | ||||||||||
Synonyms | |||||||||||
Species | Homo sapiens | ||||||||||
Ensembl Gene | ENSG00000241962 | ||||||||||
Encoded Proteins |
chromosome 2 open reading frame 15
chromosome 2 open reading frame 15
chromosome 2 open reading frame 15
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 6p and 12p. Read-through transcription also exists between this gene and the neighboring upstream lipoyltransferase 1 (LIPT1) gene. [provided by RefSeq, Mar 2011] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 2:99141485-99322741 | ||||||||||
Strand | Forward strand | ||||||||||
Band | q11.2 | ||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
No orthologs found for this gene | |||||||||||
Pathways | |||||||||||
NETPATH | |||||||||||
REACTOME | |||||||||||
KEGG |
Ribosome pathway
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INOH | |||||||||||
PID NCI | |||||||||||
Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 51263 | ||||||||||
UniGene | Hs.352211 | ||||||||||
RefSeq | NM_144706 | ||||||||||
HUGO | HGNC:28436 | ||||||||||
OMIM | 611838 | ||||||||||
CCDS | CCDS2038 | ||||||||||
HPRD | 12806 | ||||||||||
IMGT | |||||||||||
EMBL | AB051342 AC092587 AF151083 AK126402 BC000217 BC022391 CH471127 | ||||||||||
GenPept | AAF36169 AAH00217 AAH22391 AAX88929 BAB54932 BAC86542 EAX01876 EAX01878 EAX01880 EAX01881 EAX01882 EAX01883 | ||||||||||
RNA Seq Atlas | 51263 | ||||||||||