Version 5.4
Homo sapiens Gene: HAUS5
Summary
InnateDB Gene IDBG-409245.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HAUS5
Gene Name HAUS augmin-like complex, subunit 5
Synonyms dgt5; KIAA0841
Species Homo sapiens
Ensembl Gene ENSG00000249115
Encoded Proteins
IDBP-602748
HAUS augmin-like complex, subunit 5
IDBP-813456
HAUS augmin-like complex, subunit 5
IDBP-762438
IDBP-813460
HAUS augmin-like complex, subunit 5
IDBP-765578
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary HAUS5 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]
HAUS5 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb \'augmentare,\' meaning \'to increase.\' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:35612744-35625349
Strand Forward strand
Band q13.12
Transcripts
ENST00000203166 ENSP00000439056
ENST00000424522 ENSP00000475856
ENST00000428854
ENST00000430749
ENST00000588570
ENST00000585968
ENST00000590994 ENSP00000467688
ENST00000592291 ENSP00000475934
ENST00000587439 ENSP00000466661
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007067 mitotic nuclear division
GO:0051225 spindle assembly
GO:0051297 centrosome organization
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005819 spindle
GO:0005874 microtubule
GO:0070652 HAUS complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000078762
View Gene Order
ENSBTAG00000013436
Not yet available
Cross-References
SwissProt O94927
TrEMBL
UniProt Splice Variant
Entrez Gene 23354
UniGene Hs.609860 Hs.7426
RefSeq NM_015302 XM_006723119
HUGO HGNC:29130
OMIM 613432
CCDS CCDS42550
HPRD
IMGT
EMBL AB020648 BC013947 BC064390 BC157882
GenPept AAH13947 AAH64390 AAI57883 BAA74864
RNA Seq Atlas 23354

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca