Version 5.4
Homo sapiens Gene: LILRA4
Summary
InnateDB Gene IDBG-409453.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LILRA4
Gene Name leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
Synonyms CD85g; ILT7
Species Homo sapiens
Ensembl Gene ENSG00000239961
Encoded Proteins
IDBP-68564
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
IDBP-765338
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an immunoglobulin-like cell surface protein preferentially expressed in plasmacytoid dendritic cells (PDCs). This gene is highly expressed in PDCs, and is found to be rapidly down-regulated by interleukin 3 (IL3). This gene is one of the 19 highly related genes that form a leukocyte receptor gene cluster (LRC) at chromosomal region 19q13.4. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:54333185-54339150
Strand Reverse strand
Band q13.42
Transcripts
ENST00000291759 ENSP00000291759
ENST00000421056
ENST00000595581 ENSP00000471722
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002376 immune system process
Cellular Component
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
hsa04380
Osteoclast differentiation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 23547
UniGene
RefSeq NM_012276
HUGO HGNC:15503
OMIM 607517
CCDS CCDS12890
HPRD 09596
IMGT
EMBL
GenPept
RNA Seq Atlas 23547

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca