Version 5.4
Homo sapiens Gene: NLE1
Summary
InnateDB Gene IDBG-41378.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NLE1
Gene Name notchless homolog 1 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000073536
Encoded Proteins
IDBP-41380
notchless homolog 1 (Drosophila)
IDBP-375487
notchless homolog 1 (Drosophila)
IDBP-763752
IDBP-764932
IDBP-762656
IDBP-758452
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:35128753-35142315
Strand Reverse strand
Band q12
Transcripts
ENST00000360831 ENSP00000354075
ENST00000442241 ENSP00000413572
ENST00000586869 ENSP00000466588
ENST00000588642 ENSP00000465420
ENST00000593176
ENST00000588019 ENSP00000466764
ENST00000589367 ENSP00000468339
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001826 inner cell mass cell differentiation
GO:0007219 Notch signaling pathway
GO:0042273 ribosomal large subunit biogenesis
GO:0045930 negative regulation of mitotic cell cycle
GO:0061484 hematopoietic stem cell homeostasis
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020692
View Gene Order
ENSBTAG00000019094
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.85570
RefSeq NM_001014445 NM_018096 XM_005257992
HUGO
OMIM
CCDS CCDS11291 CCDS45647
HPRD 16903
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca