Version 5.4
Homo sapiens Gene: ZNF675
Summary
InnateDB Gene IDBG-41463.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF675
Gene Name zinc finger protein 675
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000197372
Encoded Proteins
IDBP-41465
zinc finger protein 675
IDBP-764176
IDBP-765344
IDBP-760788
IDBP-763726
IDBP-765377
IDBP-766307
IDBP-765210
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:23525631-23687220
Strand Reverse strand
Band p12
Transcripts
ENST00000359788 ENSP00000352836
ENST00000597074 ENSP00000472142
ENST00000601010 ENSP00000473168
ENST00000601935 ENSP00000469379
ENST00000599535 ENSP00000473035
ENST00000600299
ENST00000599168 ENSP00000469271
ENST00000600313 ENSP00000472170
ENST00000596211 ENSP00000473217
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 4 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0031625 ubiquitin protein ligase binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0019221 cytokine-mediated signaling pathway
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0043508 negative regulation of JUN kinase activity
GO:0045453 bone resorption
GO:0045671 negative regulation of osteoclast differentiation
GO:0046329 negative regulation of JNK cascade
GO:2000660 negative regulation of interleukin-1-mediated signaling pathway
GO:2000678 negative regulation of transcription regulatory region DNA binding
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0048471 perinuclear region of cytoplasm
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_12627
Generic Transcription Pathway pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL M0R373
UniProt Splice Variant
Entrez Gene 171392
UniGene Hs.264345
RefSeq NM_138330 XM_005259800 XM_005259801 XM_006722680
HUGO HGNC:30768
OMIM
CCDS CCDS32981
HPRD 18193
IMGT
EMBL AC011493 AC073544
GenPept
RNA Seq Atlas 171392

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca