Version 5.4
| Homo sapiens Gene: VCX3B | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-42220.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | VCX3B | ||||||||
| Gene Name | variable charge, X-linked 3B | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Gene | ENSG00000205642 | ||||||||
| Encoded Proteins |
variable charge, X-linked 3B
variable charge, X-linked 3B
variable charge, X-linked 3B
variable charge, X-linked 3B
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22, and the Y-linked members are two identical copies of the gene within a palindromic region on chromosome Yq11. The family members share a high degree of sequence identity, with the exception that a 30-nt unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. This family member, as represented by the reference genome allele, contains 14 copies of the 30-nt repeat unit. VCX/Y genes encode small and highly charged proteins containing putative bipartite nuclear localization signals. Although the exact function of this family member has yet to be determined, a role in mRNA stability regulation can be inferred from the ability of the highly similar family member, VCX-A, to inhibit mRNA decapping. A possible role in the regulation of ribosome assembly during spermatogenesis has also been suggested. [provided by RefSeq, Aug 2010] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome X:8464830-8466510 | ||||||||
| Strand | Forward strand | ||||||||
| Band | p22.31 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
| No orthologs found for this gene | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | B5MDK9 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 425054 | ||||||||
| UniGene | Hs.534814 | ||||||||
| RefSeq | NM_001001888 | ||||||||
| HUGO | HGNC:31838 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS48077 | ||||||||
| HPRD | 15646 | ||||||||
| IMGT | |||||||||
| EMBL | AC006062 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 425054 | ||||||||