Version 5.4
Homo sapiens Gene: C19orf40
Summary
InnateDB Gene IDBG-42397.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C19orf40
Gene Name chromosome 19 open reading frame 40
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000131944
Encoded Proteins
IDBP-42399
chromosome 19 open reading frame 40
IDBP-763978
IDBP-762312
IDBP-764767
IDBP-766291
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary FAAP24 is a component of the Fanconi anemia (FA) core complex (see MIM 227650), which plays a crucial role in DNA damage response (Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:32972209-32978222
Strand Forward strand
Band q13.11
Transcripts
ENST00000254262 ENSP00000254262
ENST00000591791
ENST00000590179 ENSP00000465728
ENST00000590281 ENSP00000468475
ENST00000589646 ENSP00000465569
ENST00000588258 ENSP00000466121
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005515 protein binding
Biological Process
GO:0006281 DNA repair
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0043231 intracellular membrane-bounded organelle
GO:0043240 Fanconi anaemia nuclear complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030493
View Gene Order
ENSBTAG00000010403
Not yet available
Pathways
NETPATH
REACTOME
REACT_18410
Fanconi Anemia pathway pathway
REACT_216
DNA Repair pathway
KEGG
INOH
PID NCI
fanconi_pathway
Fanconi anemia pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.579899
RefSeq NM_152266 XM_005259393
HUGO
OMIM
CCDS CCDS12426 CCDS74327
HPRD 14547
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca