Version 5.4
Homo sapiens Gene: ARFGAP2
Summary
InnateDB Gene IDBG-42643.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARFGAP2
Gene Name ADP-ribosylation factor GTPase activating protein 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000149182
Encoded Proteins
IDBP-372928
ADP-ribosylation factor GTPase activating protein 2
IDBP-595159
ADP-ribosylation factor GTPase activating protein 2
IDBP-600361
ADP-ribosylation factor GTPase activating protein 2
IDBP-598692
ADP-ribosylation factor GTPase activating protein 2
IDBP-583716
ADP-ribosylation factor GTPase activating protein 2
IDBP-584494
ADP-ribosylation factor GTPase activating protein 2
IDBP-598293
ADP-ribosylation factor GTPase activating protein 2
IDBP-599232
ADP-ribosylation factor GTPase activating protein 2
IDBP-600186
ADP-ribosylation factor GTPase activating protein 2
IDBP-588363
ADP-ribosylation factor GTPase activating protein 2
IDBP-601475
ADP-ribosylation factor GTPase activating protein 2
IDBP-586695
ADP-ribosylation factor GTPase activating protein 2
IDBP-587936
ADP-ribosylation factor GTPase activating protein 2
IDBP-596889
ADP-ribosylation factor GTPase activating protein 2
IDBP-586578
ADP-ribosylation factor GTPase activating protein 2
IDBP-588494
ADP-ribosylation factor GTPase activating protein 2
IDBP-604011
ADP-ribosylation factor GTPase activating protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:47164299-47177125
Strand Reverse strand
Band p11.2
Transcripts
ENST00000395449
ENST00000426335 ENSP00000400226
ENST00000524782 ENSP00000434442
ENST00000533243 ENSP00000433210
ENST00000527776 ENSP00000434022
ENST00000526342 ENSP00000437305
ENST00000527927 ENSP00000434433
ENST00000532478 ENSP00000437194
ENST00000525635
ENST00000532438 ENSP00000432978
ENST00000529455 ENSP00000434487
ENST00000524412
ENST00000525398 ENSP00000431939
ENST00000526948
ENST00000531750
ENST00000525314 ENSP00000434809
ENST00000527097
ENST00000528444 ENSP00000431684
ENST00000524727
ENST00000529599
ENST00000528041 ENSP00000437070
ENST00000529439 ENSP00000431238
ENST00000530596 ENSP00000435488
ENST00000533939
ENST00000526185
ENST00000528708 ENSP00000431847
ENST00000524586 ENSP00000433108
ENST00000530794
ENST00000528072
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
Biological Process
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0032312 regulation of ARF GTPase activity
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0000139 Golgi membrane
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027255
View Gene Order
ENSBTAG00000009574
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.436204
RefSeq NM_001242832 NM_032389
HUGO
OMIM
CCDS CCDS73283 CCDS7926
HPRD 06069
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca