Version 5.4
Homo sapiens Gene: PKD1L2
Summary
InnateDB Gene IDBG-43476.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PKD1L2
Gene Name Polycystic kidney disease protein 1-like 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000166473
Encoded Proteins
IDBP-43484
polycystic kidney disease 1-like 2
IDBP-602454
polycystic kidney disease 1-like 2
IDBP-584919
polycystic kidney disease 1-like 2
IDBP-600446
polycystic kidney disease 1-like 2
IDBP-583608
polycystic kidney disease 1-like 2
IDBP-592974
polycystic kidney disease 1-like 2
IDBP-808727
polycystic kidney disease 1-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type polymorphic_pseudogene
Genomic Location Chromosome 16:81100875-81220370
Strand Reverse strand
Band q23.2
Transcripts
ENST00000299598
ENST00000337114 ENSP00000337397
ENST00000534447
ENST00000534142
ENST00000533478 ENSP00000434644
ENST00000525539 ENSP00000434417
ENST00000530363
ENST00000529079
ENST00000531391 ENSP00000436309
ENST00000526632 ENSP00000436389
ENST00000527937 ENSP00000432818
ENST00000529791
ENST00000614230 ENSP00000483832
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0006811 ion transport
GO:0007218 neuropeptide signaling pathway
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034416
View Gene Order
ENSBTAG00000012693
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.413525 Hs.737982
RefSeq NM_001076780 NM_001278423 NM_052892
HUGO
OMIM
CCDS CCDS61998 CCDS61999
HPRD 06990
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca