Version 5.4
Homo sapiens Gene: DDX60
Summary
InnateDB Gene IDBG-43861.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DDX60
Gene Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000137628
Encoded Proteins
IDBP-242995
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
IDBP-476389
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
IDBP-474751
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
IDBP-475851
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:168216293-168318807
Strand Reverse strand
Band q32.3
Transcripts
ENST00000393743 ENSP00000377344
ENST00000511317 ENSP00000422669
ENST00000507815
ENST00000505393
ENST00000513997 ENSP00000423678
ENST00000514995 ENSP00000423647
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0003727 single-stranded RNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0008152 metabolic process
GO:0009615 response to virus
GO:0045087 innate immune response
GO:0051607 defense response to virus
GO:1900245 positive regulation of MDA-5 signaling pathway
GO:1900246 positive regulation of RIG-I signaling pathway
Cellular Component
GO:0005737 cytoplasm
GO:0045111 intermediate filament cytoskeleton
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000037921
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.481141 Hs.591710
RefSeq NM_017631
HUGO
OMIM
CCDS CCDS34097
HPRD 07877
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca