Version 5.4
Homo sapiens Gene: PALLD
Summary
InnateDB Gene IDBG-43950.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PALLD
Gene Name palladin, cytoskeletal associated protein
Synonyms CGI151; MYN; PNCA1; SIH002
Species Homo sapiens
Ensembl Gene ENSG00000129116
Encoded Proteins
IDBP-43952
palladin, cytoskeletal associated protein
IDBP-243033
palladin, cytoskeletal associated protein
IDBP-482485
palladin, cytoskeletal associated protein
IDBP-478058
palladin, cytoskeletal associated protein
IDBP-477772
palladin, cytoskeletal associated protein
IDBP-474251
palladin, cytoskeletal associated protein
IDBP-479526
palladin, cytoskeletal associated protein
IDBP-476817
palladin, cytoskeletal associated protein
IDBP-475843
palladin, cytoskeletal associated protein
IDBP-475168
palladin, cytoskeletal associated protein
IDBP-474941
palladin, cytoskeletal associated protein
IDBP-477009
palladin, cytoskeletal associated protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:168497066-168928457
Strand Forward strand
Band q32.3
Transcripts
ENST00000261509 ENSP00000261509
ENST00000393726 ENSP00000377327
ENST00000505667 ENSP00000425556
ENST00000511948 ENSP00000423640
ENST00000508898 ENSP00000423063
ENST00000504519 ENSP00000424121
ENST00000512127 ENSP00000426947
ENST00000513245 ENSP00000422016
ENST00000503457 ENSP00000424288
ENST00000510998 ENSP00000422135
ENST00000507735 ENSP00000424016
ENST00000511611
ENST00000507325
ENST00000513187
ENST00000507699
ENST00000511682
ENST00000503290 ENSP00000425729
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0051371 muscle alpha-actinin binding
Biological Process
GO:0007010 cytoskeleton organization
Cellular Component
GO:0001726 ruffle
GO:0005634 nucleus
GO:0005884 actin filament
GO:0005925 focal adhesion
GO:0030018 Z disc
GO:0030027 lamellipodium
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000058056
View Gene Order
ENSBTAG00000001081
Not yet available
Cross-References
SwissProt
TrEMBL D6R9Z5 D6RBB1 D6RBH5
UniProt Splice Variant
Entrez Gene 23022
UniGene Hs.151220 Hs.682289 Hs.707322
RefSeq NM_001166108 NM_001166109 NM_001166110 NM_016081 XM_005262862
HUGO HGNC:17068
OMIM 608092
CCDS CCDS34098 CCDS54818 CCDS54819 CCDS54820
HPRD 09731
IMGT
EMBL AC079858 AC079926 AC080188 AC084353 AC115538
GenPept
RNA Seq Atlas 23022

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca