Homo sapiens Gene: DMRT2 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-44030.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | DMRT2 | ||||||||||||||||||||||
Gene Name | doublesex and mab-3 related transcription factor 2 | ||||||||||||||||||||||
Synonyms | |||||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||||
Ensembl Gene | ENSG00000173253 | ||||||||||||||||||||||
Encoded Proteins |
doublesex and mab-3 related transcription factor 2
doublesex and mab-3 related transcription factor 2
doublesex and mab-3 related transcription factor 2
doublesex and mab-3 related transcription factor 2
doublesex and mab-3 related transcription factor 2
doublesex and mab-3 related transcription factor 2
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010] The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila \'doublesex\' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 9:1050354-1057552 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | p24.3 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||||||
SwissProt | Q9Y5R5 | ||||||||||||||||||||||
TrEMBL | Q05C20 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 10655 | ||||||||||||||||||||||
UniGene | Hs.59506 | ||||||||||||||||||||||
RefSeq | NM_001130865 NM_006557 NM_181872 XM_005251351 XM_006716717 XM_006716718 | ||||||||||||||||||||||
HUGO | HGNC:2935 | ||||||||||||||||||||||
OMIM | 604935 | ||||||||||||||||||||||
CCDS | CCDS6445 CCDS6444 | ||||||||||||||||||||||
HPRD | 16079 | ||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
EMBL | AF130729 AF284223 AF284224 AF284225 AK290794 AL358976 BC030204 BC136493 CH471071 Y19052 | ||||||||||||||||||||||
GenPept | AAD40475 AAF86291 AAF86292 AAF86293 AAF86294 AAF86295 AAH30204 AAI36494 BAF83483 CAB59891 CAH70589 EAW58816 | ||||||||||||||||||||||
RNA Seq Atlas | 10655 | ||||||||||||||||||||||