Homo sapiens Gene: FRMPD4
Summary
InnateDB Gene IDBG-44050.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FRMPD4
Gene Name FERM and PDZ domain containing 4
Synonyms PDZD10; PDZK10
Species Homo sapiens
Ensembl Gene ENSG00000169933
Encoded Proteins
FERM and PDZ domain containing 4
FERM and PDZ domain containing 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a multi-domain (WW, PDZ, FERM) containing protein. Through its interaction with other proteins (such as PSD-95), it functions as a positive regulator of dendritic spine morphogenesis and density, and is required for the maintenance of excitatory synaptic transmission. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:12138466-12724523
Strand Forward strand
Band p22.2
Transcripts
ENST00000380682 ENSP00000370057
ENST00000616992 ENSP00000482182
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
Biological Process
GO:0051835 positive regulation of synapse structural plasticity
Cellular Component
GO:0005856 cytoskeleton
GO:0043197 dendritic spine
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 9758
UniGene
RefSeq NM_014728 XM_005274632
HUGO HGNC:29007
OMIM 300838
CCDS CCDS35201
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 9758