Version 5.4
Homo sapiens Gene: HSPA4
Summary
InnateDB Gene IDBG-44104.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSPA4
Gene Name heat shock 70kDa protein 4
Synonyms APG-2; HEL-S-5a; HS24/P52; hsp70; hsp70RY; HSPH2; RY
Species Homo sapiens
Ensembl Gene ENSG00000170606
Encoded Proteins
IDBP-44106
heat shock 70kDa protein 4
IDBP-806990
heat shock 70kDa protein 4
IDBP-806992
heat shock 70kDa protein 4
IDBP-806999
heat shock 70kDa protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:133051962-133106449
Strand Forward strand
Band q31.1
Transcripts
ENST00000304858 ENSP00000302961
ENST00000504328
ENST00000514825
ENST00000617819 ENSP00000480688
ENST00000617074 ENSP00000481686
ENST00000615899 ENSP00000478102
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 340 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 340 [view]
Protein-Protein 340 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0000902 cell morphogenesis
GO:0006986 response to unfolded protein
GO:0045040 protein import into mitochondrial outer membrane
GO:0051131 chaperone-mediated protein complex assembly
Cellular Component
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020361
View Gene Order
ENSBTAG00000015683
Not yet available
Pathways
NETPATH
NetPath_2
AndrogenReceptor pathway
NetPath_4
EGFR1 pathway
REACTOME
KEGG
hsa04612
Antigen processing and presentation pathway
INOH
PID NCI
myc_activpathway
Validated targets of C-MYC transcriptional activation
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_002154
HUGO
OMIM
CCDS CCDS4166
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca