Homo sapiens Gene: SLC16A7 | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||||||||||
InnateDB Gene | IDBG-44219.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | SLC16A7 | ||||||||||||||||||
Gene Name | solute carrier family 16, member 7 (monocarboxylic acid transporter 2) | ||||||||||||||||||
Synonyms | MCT2 | ||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000118596 | ||||||||||||||||||
Encoded Proteins |
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
|
||||||||||||||||||
Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012] |
||||||||||||||||||
Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 12:59596067-59789855 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | q14.1 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
|
||||||||||||||||||
Gene Ontology | |||||||||||||||||||
Molecular Function |
|
||||||||||||||||||
Biological Process |
|
||||||||||||||||||
Cellular Component |
|
||||||||||||||||||
Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||||||||||||
Pathways | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
Proton-coupled monocarboxylate transport pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
|
||||||||||||||||||
KEGG | |||||||||||||||||||
INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | |||||||||||||||||||
UniGene | Hs.589104 Hs.88156 | ||||||||||||||||||
RefSeq | NM_001270622 NM_001270623 NM_004731 XM_005269231 XM_006719693 | ||||||||||||||||||
HUGO | |||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | CCDS8961 | ||||||||||||||||||
HPRD | 06791 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | |||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||