Version 5.4
Homo sapiens Gene: FEZ2
Summary
InnateDB Gene IDBG-44299.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FEZ2
Gene Name fasciculation and elongation protein zeta 2 (zygin II)
Synonyms HUM3CL
Species Homo sapiens
Ensembl Gene ENSG00000171055
Encoded Proteins
IDBP-44301
fasciculation and elongation protein zeta 2 (zygin II)
IDBP-44303
fasciculation and elongation protein zeta 2 (zygin II)
IDBP-44305
fasciculation and elongation protein zeta 2 (zygin II)
IDBP-294097
fasciculation and elongation protein zeta 2 (zygin II)
IDBP-372305
fasciculation and elongation protein zeta 2 (zygin II)
IDBP-372308
fasciculation and elongation protein zeta 2 (zygin II)
IDBP-372309
fasciculation and elongation protein zeta 2 (zygin II)
IDBP-372310
fasciculation and elongation protein zeta 2 (zygin II)
IDBP-372311
fasciculation and elongation protein zeta 2 (zygin II)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes zygin II, which can bind to synaptotagmin. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:36531805-36646087
Strand Reverse strand
Band p22.2
Transcripts
ENST00000357996 ENSP00000350685
ENST00000379245 ENSP00000368547
ENST00000305852 ENSP00000305843
ENST00000405912 ENSP00000385112
ENST00000414288 ENSP00000395619
ENST00000413938 ENSP00000410879
ENST00000441005 ENSP00000415325
ENST00000451623 ENSP00000390985
ENST00000432869 ENSP00000396982
ENST00000475815
ENST00000487919
ENST00000487282
ENST00000484205
ENST00000464964
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0007399 nervous system development
GO:0007411 axon guidance
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000056121
View Gene Order
ENSBTAG00000009021
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.258563
RefSeq NM_001042548 NM_005102 XM_006712153
HUGO
OMIM
CCDS CCDS46257 CCDS46258
HPRD 09213
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca