Version 5.4
Homo sapiens Gene: TRAPPC2
Summary
InnateDB Gene IDBG-44932.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRAPPC2
Gene Name trafficking protein particle complex 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000196459
Encoded Proteins
IDBP-44936
trafficking protein particle complex 2
IDBP-44940
trafficking protein particle complex 2
IDBP-362177
trafficking protein particle complex 2
IDBP-479053
trafficking protein particle complex 2
IDBP-479147
trafficking protein particle complex 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:13712244-13734635
Strand Reverse strand
Band p22.2
Transcripts
ENST00000359680 ENSP00000352708
ENST00000380579 ENSP00000369953
ENST00000380578
ENST00000458511 ENSP00000392495
ENST00000519382
ENST00000517553
ENST00000519885 ENSP00000430725
ENST00000518847 ENSP00000428900
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 26 [view]
Protein-Protein 26 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0044325 ion channel binding
Biological Process
GO:0001501 skeletal system development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006810 transport
GO:0006888 ER to Golgi vesicle-mediated transport
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005801 cis-Golgi network
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000079317
View Gene Order
Cross-References
SwissProt P0DI81
TrEMBL E5RFG0 Q6IBE5
UniProt Splice Variant
Entrez Gene 6399
UniGene Hs.592238 Hs.622292 Hs.630805 Hs.634785
RefSeq NM_001128835 NM_001011658 NM_014563
HUGO HGNC:23068
OMIM 300202
CCDS CCDS48083 CCDS48082
HPRD 02189
IMGT
EMBL AC003002 AC003037 AF058918 AF157062 AF157063 AF157064 AF157065 AF291676 AK310542 AK313736 BC008889 BC016915 BC032809 BC052618 CH471074 CH471135 CR456859 DA542477 DB101396
GenPept AAB80684 AAC14421 AAD49845 AAG02469 AAH16915 AAH52618 BAG36477 CAG33140 EAW72495 EAW72496 EAW98829 EAW98830 EAW98831 EAW98832 EAW98834
RNA Seq Atlas 6399

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca