Version 5.4
Homo sapiens Gene: ADARB2
Summary
InnateDB Gene IDBG-45374.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADARB2
Gene Name adenosine deaminase, RNA-specific, B2
Synonyms ADAR3; RED2
Species Homo sapiens
Ensembl Gene ENSG00000185736
Encoded Proteins
IDBP-45376
adenosine deaminase, RNA-specific, B2
IDBP-45378
adenosine deaminase, RNA-specific, B2
IDBP-45384
adenosine deaminase, RNA-specific, B2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the double-stranded RNA adenosine deaminase family of RNA-editing enzymes and may play a regulatory role in RNA editing. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:1177318-1737476
Strand Reverse strand
Band p15.3
Transcripts
ENST00000381312 ENSP00000370713
ENST00000381310 ENSP00000370711
ENST00000381305 ENSP00000370706
ENST00000474762
ENST00000490172
ENST00000477140
ENST00000469464
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0003727 single-stranded RNA binding
GO:0004000 adenosine deaminase activity
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006396 RNA processing
GO:0006397 mRNA processing
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000052551
View Gene Order
ENSBTAG00000014194
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.586663
RefSeq NM_018702
HUGO
OMIM
CCDS CCDS7058
HPRD 09070
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca