Homo sapiens Gene: ADARB2

Summary
InnateDB Gene IDBG-45374.5
Last Modified 2012-02-14   [Report errors or provide feedback]
Gene Symbol ADARB2
Gene Name adenosine deaminase, RNA-specific, B2
Synonyms ADAR3; RED2
Species Homo sapiens
Ensembl Gene ENSG00000185736
Encoded Proteins
IDBP-45376 adenosine deaminase, RNA-specific, B2
IDBP-45378 adenosine deaminase, RNA-specific, B2
IDBP-45384 adenosine deaminase, RNA-specific, B2
Entrez Gene
Summary This gene encodes a member of the double-stranded RNA adenosine deaminase family of RNA-editing enzymes and may play a regulatory role in RNA editing. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10: 1228073-1779670
Strand Reverse strand
Band p15.3
Transcripts
ENST00000381312  ENSP00000370713
ENST00000381310  ENSP00000370711
ENST00000381305  ENSP00000370706
ENST00000474762 
ENST00000490172 
ENST00000477140 
ENST00000469464 
Interactions
Number of Interactions   This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein‑Protein  1
[view]
Protein‑DNA 0
Protein‑RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
 
Gene Ontology
Accession GO Term
Molecular Function
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0003727 single-stranded RNA binding
GO:0004000 adenosine deaminase activity
GO:0046872 metal ion binding
Biological Process
GO:0006396 RNA processing
GO:0006397 mRNA processing
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID Gene Order Method Confidence Comments
ENSMUSG00000052551 Ortholuge Non-SSD Ortholog Possible paralog/unusual divergence/ gene prediction error
ENSBTAG00000014194 Not yet available Ortholuge Non-SSD Ortholog Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9NS39 
TrEMBL Q5VW42 Q5VW43
UniProt Splice Variant
Entrez Gene 105 
UniGene Hs.586663
RefSeq NM_018702 
HUGO 227 
OMIM 602065
CCDS CCDS7058 
HPRD 09070
IMGT
EMBL AC026224 AF034837 AK055107 AL392083 AL442069 AL450386 AL513304 BC137477 BC140852
GenPept AAF78094  AAI37478  AAI40853  BAG51468  CAH72169  CAH72170  CAH72171  CAH73405 
ImmGen ADARB2 (murine) 
RNA Seq Atlas 105