Version 5.4
Homo sapiens Gene: WDR62
Summary
InnateDB Gene IDBG-46287.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WDR62
Gene Name WD repeat domain 62
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000075702
Encoded Proteins
IDBP-46291
WD repeat domain 62
IDBP-295219
WD repeat domain 62
IDBP-378639
WD repeat domain 62
IDBP-761534
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 19910486
WDR62 is recruited to stress granules and mediates a non-classical MAPK8 (JNK) activation.
Entrez Gene
Summary This gene is proposed to play a role in cerebral cortical development. Mutations in this gene have been associated with microencephaly, cortical malformations, and mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:36054881-36105106
Strand Forward strand
Band q13.12
Transcripts
ENST00000378860
ENST00000270301 ENSP00000270301
ENST00000401500 ENSP00000384792
ENST00000427823 ENSP00000413475
ENST00000587391 ENSP00000465525
ENST00000589953
ENST00000608676
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0021987 cerebral cortex development
GO:0022008 neurogenesis
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037020
View Gene Order
ENSBTAG00000014996
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.116244
RefSeq NM_001083961 NM_173636
HUGO
OMIM
CCDS CCDS33001 CCDS46059
HPRD 10721
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca