Version 5.4
Homo sapiens Gene: MINA
Summary
InnateDB Gene IDBG-46577.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MINA
Gene Name MYC induced nuclear antigen
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000170854
Encoded Proteins
IDBP-46579
MYC induced nuclear antigen
IDBP-46581
MYC induced nuclear antigen
IDBP-242076
MYC induced nuclear antigen
IDBP-475331
MYC induced nuclear antigen
IDBP-484692
MYC induced nuclear antigen
IDBP-485323
MYC induced nuclear antigen
IDBP-485054
MYC induced nuclear antigen
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary MINA is a c-Myc (MYC; MIM 190080) target gene that may play a role in cell proliferation or regulation of cell growth. (Tsuneoka et al., 2002 [PubMed 12091391]; Zhang et al., 2005 [PubMed 15897898]).[supplied by OMIM, May 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:97941818-97972457
Strand Reverse strand
Band q11.2
Transcripts
ENST00000333396 ENSP00000328251
ENST00000360258 ENSP00000353395
ENST00000394198 ENSP00000377748
ENST00000506682
ENST00000503517
ENST00000503097 ENSP00000421347
ENST00000514314 ENSP00000424955
ENST00000507612 ENSP00000424530
ENST00000506099 ENSP00000423816
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001191 RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0042254 ribosome biogenesis
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022724
View Gene Order
ENSBTAG00000015546
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
myc_activpathway
Validated targets of C-MYC transcriptional activation
Cross-References
SwissProt
TrEMBL H0Y8K4
UniProt Splice Variant
Entrez Gene 84864
UniGene Hs.570562 Hs.742206
RefSeq NM_001042533 NM_001261829 NM_032778 NM_153182
HUGO HGNC:19441
OMIM 612049
CCDS CCDS2929 CCDS43114
HPRD 17575
IMGT
EMBL AC026100 AC110491
GenPept
RNA Seq Atlas 84864

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca