Version 5.4
Homo sapiens Gene: NOBOX
Summary
InnateDB Gene IDBG-46656.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NOBOX
Gene Name NOBOX oogenesis homeobox
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000106410
Encoded Proteins
IDBP-477408
NOBOX oogenesis homeobox
IDBP-479191
NOBOX oogenesis homeobox
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This homeobox gene encodes a transcription factor that is thought to play a role in oogenesis. In mice, it is essential for folliculogenesis and regulation of oocyte-specific genes. Defects in this gene result in premature ovarian failure type 5.[provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:144397240-144410227
Strand Reverse strand
Band q35
Transcripts
ENST00000483238 ENSP00000419565
ENST00000467773 ENSP00000419457
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001541 ovarian follicle development
GO:0006351 transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048477 oogenesis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029736
View Gene Order
ENSBTAG00000009832
Not yet available
Cross-References
SwissProt O60393
TrEMBL
UniProt Splice Variant
Entrez Gene 135935
UniGene Hs.558628
RefSeq NM_001080413
HUGO HGNC:22448
OMIM 610934
CCDS
HPRD
IMGT
EMBL AC004534
GenPept AAC12957
RNA Seq Atlas 135935

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca