Version 5.4
Homo sapiens Gene: INSL6
Summary
InnateDB Gene IDBG-47235.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INSL6
Gene Name insulin-like 6
Synonyms RIF1
Species Homo sapiens
Ensembl Gene ENSG00000120210
Encoded Proteins
IDBP-47237
insulin-like 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. This gene is preferentially expressed in testis. Its expression in testis is restricted to interstitial cells surrounding seminiferous tubules, which suggests a role in sperm development and fertilization. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:5131979-5185668
Strand Reverse strand
Band p24.1
Transcripts
ENST00000381641 ENSP00000371054
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
Biological Process
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0008150 biological_process
GO:0008584 male gonad development
GO:0009566 fertilization
GO:0030317 sperm motility
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000050957
View Gene Order
ENSBTAG00000006651
Not yet available
Cross-References
SwissProt Q9Y581
TrEMBL
UniProt Splice Variant
Entrez Gene 11172
UniGene
RefSeq NM_007179
HUGO HGNC:6089
OMIM 606414
CCDS CCDS6458
HPRD
IMGT
EMBL AF135824 AF156094 AL161450 BC126473 BC126475
GenPept AAD39003 AAF29604 AAI26474 AAI26476 CAD13336
RNA Seq Atlas 11172

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca