Version 5.4
Homo sapiens Gene: INSL4
Summary
InnateDB Gene IDBG-47285.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INSL4
Gene Name insulin-like 4 (placenta)
Synonyms EPIL; PLACENTIN
Species Homo sapiens
Ensembl Gene ENSG00000120211
Encoded Proteins
IDBP-47287
insulin-like 4 (placenta)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary INSL4 encodes the insulin-like 4 protein, a member of the insulin superfamily. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains, or just the A and B chains. Expression of INSL4 products occurs within the early placental cytotrophoblast and syncytiotrophoblast. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:5231419-5235304
Strand Forward strand
Band p24.1
Transcripts
ENST00000239316 ENSP00000239316
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005159 insulin-like growth factor receptor binding
GO:0005179 hormone activity
Biological Process
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0007275 multicellular organismal development
GO:0007565 female pregnancy
GO:0008283 cell proliferation
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q14641
TrEMBL
UniProt Splice Variant
Entrez Gene 3641
UniGene
RefSeq NM_002195
HUGO HGNC:6087
OMIM 600910
CCDS CCDS6459
HPRD
IMGT
EMBL AK291543 AL133547 BC026254 CH471071 L34838
GenPept AAB08516 AAH26254 BAF84232 CAH70506 EAW58772
RNA Seq Atlas 3641

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca