Homo sapiens Gene: TSPAN8 | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Gene | IDBG-47950.6 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | TSPAN8 | ||||||||||||||
Gene Name | tetraspanin 8 | ||||||||||||||
Synonyms | CO-029; TM4SF3 | ||||||||||||||
Species | Homo sapiens | ||||||||||||||
Ensembl Gene | ENSG00000127324 | ||||||||||||||
Encoded Proteins |
tetraspanin 8
tetraspanin 8
tetraspanin 8
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Protein Structure | |||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
Entrez Gene | |||||||||||||||
Summary |
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||
Type | Protein coding | ||||||||||||||
Genomic Location | Chromosome 12:71125085-71441898 | ||||||||||||||
Strand | Reverse strand | ||||||||||||||
Band | q21.1 | ||||||||||||||
Transcripts |
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Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||
SwissProt | P19075 | ||||||||||||||
TrEMBL | |||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | 7103 | ||||||||||||||
UniGene | Hs.170563 | ||||||||||||||
RefSeq | NM_004616 XM_006719583 | ||||||||||||||
HUGO | HGNC:11855 | ||||||||||||||
OMIM | 600769 | ||||||||||||||
CCDS | CCDS8999 | ||||||||||||||
HPRD | 02865 | ||||||||||||||
IMGT | |||||||||||||||
EMBL | AK313112 BC005246 CH471054 M35252 | ||||||||||||||
GenPept | AAA35709 AAH05246 BAG35934 EAW97257 | ||||||||||||||
RNA Seq Atlas | 7103 | ||||||||||||||