InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: MTA3

Summary

InnateDB Gene

IDBG-48544.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MTA3

Gene Name

metastasis associated 1 family, member 3

Synonyms

Species

Homo sapiens

Ensembl Gene

ENSG00000057935

Encoded Proteins

IDBP-293814

metastasis associated 1 family, member 3

IDBP-293811

metastasis associated 1 family, member 3

IDBP-293821

metastasis associated 1 family, member 3

IDBP-293820

metastasis associated 1 family, member 3

IDBP-293812

metastasis associated 1 family, member 3

IDBP-293816

metastasis associated 1 family, member 3

IDBP-373831

metastasis associated 1 family, member 3

IDBP-373839

metastasis associated 1 family, member 3

IDBP-373850

metastasis associated 1 family, member 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:42494569-42756947

Strand

Forward strand

Band

p21

Transcripts

ENST00000405094	ENSP00000385823
ENST00000409019	ENSP00000386763
ENST00000407270	ENSP00000385045
ENST00000406911	ENSP00000385241
ENST00000405592	ENSP00000383973
ENST00000406652	ENSP00000384249
ENST00000454356	ENSP00000391455
ENST00000430763	ENSP00000401815
ENST00000433553	ENSP00000388722
ENST00000484780
ENST00000461256
ENST00000493983
ENST00000491314
ENST00000490611
ENST00000472767
ENST00000475383
ENST00000482875
ENST00000467925
ENST00000478602

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 45 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	45 [view]
Protein-Protein	44 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0008284	positive regulation of cell proliferation
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0008278	cohesin complex
GO:0016581	NuRD complex
GO:0043231	intracellular membrane-bounded organelle

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000055817

View Gene Order

ENSBTAG00000004073

Not yet available

Pathways

NETPATH

REACTOME

REACT_953

RNA Polymerase I Transcription Initiation pathway

REACT_1309

RNA Polymerase I Transcription pathway

REACT_1974

RNA Polymerase I Promoter Clearance pathway

REACT_228222

HDACs deacetylate histones pathway

REACT_172623

Chromatin organization pathway

REACT_172633

Chromatin modifying enzymes pathway

REACT_21352

RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway

REACT_71

Gene Expression pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

E9PCS8 Q53RX8 Q53SC0

UniProt Splice Variant

Entrez Gene

57504

UniGene

Hs.435413 Hs.603284 Hs.627028 Hs.646800 Hs.743512

RefSeq

NM_001282755 NM_001282756 NM_020744 XM_005264456 XM_005264458 XM_005264459

HUGO

HGNC:23784

OMIM

609050

CCDS

CCDS46267 CCDS62900

HPRD

12359

IMGT

EMBL

AC025750 AC074375 AC093386 AC098824

GenPept

AAY24040 AAY24110

RNA Seq Atlas

57504