InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: GPR64

Summary

InnateDB Gene

IDBG-49134.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GPR64

Gene Name

G protein-coupled receptor 64

Synonyms

EDDM6; HE6; TM7LN2

Species

Homo sapiens

Ensembl Gene

ENSG00000173698

Encoded Proteins

IDBP-49136

G protein-coupled receptor 64

IDBP-49138

G protein-coupled receptor 64

IDBP-49140

G protein-coupled receptor 64

IDBP-49142

G protein-coupled receptor 64

IDBP-49144

G protein-coupled receptor 64

IDBP-49146

G protein-coupled receptor 64

IDBP-49148

G protein-coupled receptor 64

IDBP-49150

G protein-coupled receptor 64

IDBP-49152

G protein-coupled receptor 64

IDBP-49156

G protein-coupled receptor 64

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes a member of the G protein-coupled receptor family described as an epididymis-specific transmembrane protein. The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:18989309-19122637

Strand

Reverse strand

Band

p22.13

Transcripts

ENST00000340581	ENSP00000344972
ENST00000379878	ENSP00000369207
ENST00000354791	ENSP00000346845
ENST00000356606	ENSP00000349015
ENST00000379876	ENSP00000369205
ENST00000379873	ENSP00000369202
ENST00000379869	ENSP00000369198
ENST00000360279	ENSP00000353421
ENST00000357544	ENSP00000350152
ENST00000357991	ENSP00000350680
ENST00000479496

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0004930	G-protein coupled receptor activity

Biological Process

GO:0007166	cell surface receptor signaling pathway
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007218	neuropeptide signaling pathway
GO:0007283	spermatogenesis

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0070062	extracellular vesicular exosome

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000031298

View Gene Order

ENSBTAG00000000576

Not yet available

Cross-References

SwissProt

Q8IZP9

TrEMBL

UniProt Splice Variant

Entrez Gene

10149

UniGene

Hs.146978

RefSeq

NM_001184837 XM_006724454 NM_001079858 NM_001079859 NM_001079860 NM_001184833 NM_001184834 NM_001184835 NM_001184836 NM_005756 XM_006724449 XM_006724450 XM_006724451 XM_006724452 XM_006724453 XM_006724455 XM_006724456

HUGO

HGNC:4516

OMIM

300572

CCDS

CCDS55377 CCDS14191 CCDS43921 CCDS43922 CCDS43923 CCDS55376 CCDS55378 CCDS55379

HPRD

04040

IMGT

EMBL

AF538954 AF539455 AF539456 AL732509 AL732578 AY143364 AY143365 AY143366 AY143367 AY148343 BC113979 X81892

GenPept

AAI13980 AAN33056 AAN33064 AAN33065 AAN38971 AAN38972 AAN38973 AAN38974 AAN75702 CAA57479 CAI40668 CAI40669 CAI40670 CAI40671 CAI41675 CAI41676 CAI41677 CAI41678

RNA Seq Atlas

10149