Homo sapiens Gene: DAOA | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-49464.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | DAOA | ||||||
Gene Name | D-amino acid oxidase activator | ||||||
Synonyms | |||||||
Species | Homo sapiens | ||||||
Ensembl Gene | ENSG00000182346 | ||||||
Encoded Proteins |
D-amino acid oxidase activator
D-amino acid oxidase activator
D-amino acid oxidase activator
D-amino acid oxidase activator
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Mar 2011] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 13:105465867-105491034 | ||||||
Strand | Forward strand | ||||||
Band | q33.2 | ||||||
Transcripts | |||||||
Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
No orthologs found for this gene | |||||||
Cross-References | |||||||
SwissProt | P59103 | ||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 267012 | ||||||
UniGene | Hs.381382 | ||||||
RefSeq | NM_001161814 NM_001161812 NM_172370 XM_005254042 | ||||||
HUGO | HGNC:21191 | ||||||
OMIM | 607408 | ||||||
CCDS | CCDS53880 CCDS41905 CCDS59242 | ||||||
HPRD | 07591 | ||||||
IMGT | |||||||
EMBL | AE014294 AL359751 AY138546 AY138547 AY170469 AY223901 BC121091 CH471085 DQ343761 DQ357223 | ||||||
GenPept | AAI21092 AAN08432 AAN08433 AAN16027 AAN16028 AAO12727 AAO73604 ABC59904 ABC86111 CAH70815 EAX09080 | ||||||
RNA Seq Atlas | 267012 | ||||||