Version 5.4
Homo sapiens Gene: CNDP2
Summary
InnateDB Gene IDBG-5004.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CNDP2
Gene Name CNDP dipeptidase 2 (metallopeptidase M20 family)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000133313
Encoded Proteins
IDBP-5008
CNDP dipeptidase 2 (metallopeptidase M20 family)
IDBP-5010
CNDP dipeptidase 2 (metallopeptidase M20 family)
IDBP-727997
IDBP-725696
IDBP-811068
CNDP dipeptidase 2 (metallopeptidase M20 family)
IDBP-727970
IDBP-726846
IDBP-726551
IDBP-726852
IDBP-726894
IDBP-811067
CNDP dipeptidase 2 (metallopeptidase M20 family)
IDBP-727006
IDBP-727904
IDBP-728059
IDBP-726815
IDBP-727152
IDBP-726974
IDBP-725768
IDBP-727379
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003 [PubMed 12473676]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:74495816-74523454
Strand Forward strand
Band q22.3
Transcripts
ENST00000324262 ENSP00000325548
ENST00000324301 ENSP00000325756
ENST00000583399
ENST00000583695
ENST00000579847 ENSP00000462311
ENST00000583938
ENST00000581912 ENSP00000462626
ENST00000577355 ENSP00000479635
ENST00000577600 ENSP00000463816
ENST00000580672 ENSP00000464214
ENST00000583216 ENSP00000462673
ENST00000579583 ENSP00000464122
ENST00000582589 ENSP00000463182
ENST00000584581
ENST00000584768 ENSP00000482227
ENST00000582666 ENSP00000461941
ENST00000581513 ENSP00000463702
ENST00000580229
ENST00000577409
ENST00000581272 ENSP00000464151
ENST00000583203 ENSP00000463314
ENST00000577669
ENST00000583785 ENSP00000463222
ENST00000582620
ENST00000585263
ENST00000582260 ENSP00000464319
ENST00000579624 ENSP00000462034
ENST00000581600
ENST00000584613 ENSP00000464014
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
Experimentally validated
Total 39 [view]
Protein-Protein 37 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004180 carboxypeptidase activity
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0016787 hydrolase activity
GO:0016805 dipeptidase activity
GO:0034701 tripeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0000096 sulfur amino acid metabolic process
GO:0006508 proteolysis
GO:0006750 glutathione biosynthetic process
GO:0006805 xenobiotic metabolic process
GO:0008152 metabolic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0044281 small molecule metabolic process
GO:1901687 glutathione derivative biosynthetic process
Cellular Component
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024644
View Gene Order
ENSBTAG00000009841
Not yet available
Pathways
NETPATH
REACTOME
REACT_115639
Sulfur amino acid metabolism pathway
REACT_6960
Glutathione synthesis and recycling pathway
REACT_6926
Glutathione conjugation pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_6959
Phase II conjugation pathway
REACT_111217
Metabolism pathway
REACT_13433
Biological oxidations pathway
KEGG
hsa00340
Histidine metabolism pathway
hsa00330
Arginine and proline metabolism pathway
hsa00410
beta-Alanine metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.149185 Hs.711198
RefSeq NM_001168499 NM_018235 XM_005266728 XM_006722502 XM_006722503
HUGO
OMIM
CCDS CCDS12006 CCDS54190
HPRD 09893
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca