Version 5.4
Homo sapiens Gene: CPSF7
Summary
InnateDB Gene IDBG-50138.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CPSF7
Gene Name cleavage and polyadenylation specific factor 7, 59kDa
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000149532
Encoded Proteins
IDBP-50140
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-240674
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-375638
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-375639
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-375641
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-375643
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-375644
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-375646
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-589059
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-587650
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-594974
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-600538
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-597167
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-592487
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-588940
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-584830
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-589184
cleavage and polyadenylation specific factor 7, 59kDa
IDBP-592756
cleavage and polyadenylation specific factor 7, 59kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:61402641-61430031
Strand Reverse strand
Band q12.2
Transcripts
ENST00000340437 ENSP00000345412
ENST00000394888 ENSP00000378352
ENST00000439958 ENSP00000397203
ENST00000448745 ENSP00000407394
ENST00000413232 ENSP00000393828
ENST00000450000 ENSP00000391359
ENST00000449811 ENSP00000392400
ENST00000413184 ENSP00000414295
ENST00000477890 ENSP00000437860
ENST00000494016
ENST00000463244
ENST00000489728
ENST00000474684
ENST00000537641
ENST00000544669
ENST00000539952 ENSP00000438381
ENST00000535222 ENSP00000446193
ENST00000544990 ENSP00000440414
ENST00000544585 ENSP00000437531
ENST00000537162 ENSP00000442819
ENST00000543545 ENSP00000443504
ENST00000541963 ENSP00000446330
ENST00000536548 ENSP00000437467
ENST00000536145 ENSP00000437768
ENST00000545934
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 51 experimentally validated interaction(s) in this database.
Experimentally validated
Total 51 [view]
Protein-Protein 51 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006366 transcription from RNA polymerase II promoter
GO:0006369 termination of RNA polymerase II transcription
GO:0008380 RNA splicing
GO:0010467 gene expression
GO:0031124 mRNA 3'-end processing
GO:0051262 protein tetramerization
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005849 mRNA cleavage factor complex
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034820
View Gene Order
ENSBTAG00000015263
Not yet available
Pathways
NETPATH
REACTOME
REACT_1096
Processing of Intronless Pre-mRNAs pathway
REACT_1849
mRNA 3'-end processing pathway
REACT_467
mRNA Splicing - Major Pathway pathway
REACT_125
Processing of Capped Intron-Containing Pre-mRNA pathway
REACT_387
Cleavage of Growing Transcript in the Termination Region pathway
REACT_894
RNA Polymerase II Transcription Termination pathway
REACT_1366
RNA Polymerase II Transcription pathway
REACT_1768
Processing of Capped Intronless Pre-mRNA pathway
REACT_1735
mRNA Splicing pathway
REACT_71
Gene Expression pathway
KEGG
hsa03015
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F5H5B7
UniProt Splice Variant
Entrez Gene 79869
UniGene Hs.743431
RefSeq NM_001136040 NM_001142565 NM_024811 XM_005274298 XM_005274299 XM_006718690 XM_006718691
HUGO HGNC:30098
OMIM
CCDS CCDS44619 CCDS44620 CCDS8006
HPRD 16906
IMGT
EMBL AP003108
GenPept
RNA Seq Atlas 79869

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca