Version 5.4
Homo sapiens Gene: MED29
Summary
InnateDB Gene IDBG-50290.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MED29
Gene Name mediator complex subunit 29
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000063322
Encoded Proteins
IDBP-50292
mediator complex subunit 29
IDBP-764153
IDBP-759735
IDBP-765823
IDBP-765161
IDBP-763343
IDBP-810801
mediator complex subunit 29
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary MED29 is a subunit of the Mediator complex, a multiprotein coactivator of RNA transcription that interacts with DNA-bound transcriptional activators, RNA polymerase II (see MIM 180660), and general initiation factors (Sato et al., 2003 [PubMed 14576168]).[supplied by OMIM, Aug 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:39391303-39400637
Strand Forward strand
Band q13.2
Transcripts
ENST00000315588 ENSP00000314343
ENST00000594368 ENSP00000472501
ENST00000596297 ENSP00000473181
ENST00000599417 ENSP00000471101
ENST00000600973 ENSP00000471444
ENST00000599213 ENSP00000471802
ENST00000615911 ENSP00000481733
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 80 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 80 [view]
Protein-Protein 80 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0016592 mediator complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000003444
View Gene Order
ENSBTAG00000020429
Not yet available
Pathways
NETPATH
REACTOME
REACT_116145
PPARA activates gene expression pathway
REACT_19241
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_27161
Transcriptional regulation of white adipocyte differentiation pathway
REACT_111045
Developmental Biology pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL M0R0U2
UniProt Splice Variant
Entrez Gene 55588
UniGene Hs.611541 Hs.669756
RefSeq NM_017592
HUGO HGNC:23074
OMIM 612914
CCDS CCDS33021
HPRD 13748
IMGT
EMBL AC005239 AC011500 AC104106
GenPept
RNA Seq Atlas 55588

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca