Version 5.4
Homo sapiens Gene: PAX9
Summary
InnateDB Gene IDBG-5047.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PAX9
Gene Name paired box 9
Synonyms STHAG3
Species Homo sapiens
Ensembl Gene ENSG00000198807
Encoded Proteins
IDBP-5049
paired box 9
IDBP-294694
paired box 9
IDBP-588391
paired box 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 9 gene is unknown but it may involve development of stratified squamous epithelia as well as various organs and skeletal elements. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:36657568-36679715
Strand Forward strand
Band q13.3
Transcripts
ENST00000361487 ENSP00000355245
ENST00000402703 ENSP00000384817
ENST00000554201 ENSP00000450434
ENST00000557107
ENST00000553267
ENST00000555639
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007492 endoderm development
GO:0042476 odontogenesis
GO:0042481 regulation of odontogenesis
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0060325 face morphogenesis
GO:0071363 cellular response to growth factor stimulus
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000001497
View Gene Order
ENSBTAG00000009186
Not yet available
Cross-References
SwissProt P55771
TrEMBL E9KY40 Q2L4T1 Q7Z4A7
UniProt Splice Variant
Entrez Gene 5083
UniGene Hs.132576 Hs.609574 Hs.659970
RefSeq NM_006194
HUGO HGNC:8623
OMIM 167416
CCDS CCDS9662
HPRD 01336
IMGT
EMBL AB248958 AJ238381 AJ238382 AJ238383 AY338688 BC001159 CH471078 HM214021 HM214022 HM214023 HM214024 HM214025 HM214026 HM214027 HM214028 HM214029 HM214030 HM214031 HM214032 HM214033 HM214034 HM214035 HM214036 HM214037 HM214038 HM214039 HM214040 HM214041 HM214042 HM214043 HM214044 HM214045 HM214046 HM214047 HM214048 HM214051 HM214052 HM214054 HM214055 HM214056 HM214057 HM214059 HM214060 HM214061 HM214062 HM214063 HM214065 HM214067 HM214068 HM214069 HM214070 HM214071 HM214072 HM214073 HM214074 HM214075 HM214077 HM214079 HM214080 HM214081 HM214082 HM214085 HM214087 HM214088 HM214089 HM214090 HM214091 HM214092 HM214093 HM214094 HM214095 HM214096 HM214097 HM214099 HM214100 HM214101 HM214102 HM214103 HM214104 HM214106 HM214107 HM214108 HM214109 HM214110 HM214111 HM214114 HM214116 HM214118 HM214119 HM214120 HM214121 HM214122 HM214123 HM214124 HM214125 HM214126 HM214127 HM214128 HM214129 HM214130 HM214131 HM214132 HM214133 HM214134 HM214135 HM214136 HM214137 HM214138 HM214139 HM214140 L09745 X92850
GenPept AAH01159 AAQ16120 ADR64954 ADR64955 ADR64956 ADR64957 ADR64958 ADR64959 ADR64960 ADR64961 ADR64962 ADR64963 ADR64964 ADR64965 ADR64966 ADR64967 ADR64968 ADR64969 ADR64970 ADR64971 ADR64972 ADR64973 ADR64974 ADR64975 ADR64976 ADR64977 ADR64978 ADR64979 ADR64980 ADR64981 ADR64984 ADR64985 ADR64987 ADR64988 ADR64989 ADR64990 ADR64992 ADR64993 ADR64994 ADR64995 ADR64996 ADR64998 ADR65000 ADR65001 ADR65002 ADR65003 ADR65004 ADR65005 ADR65006 ADR65007 ADR65008 ADR65010 ADR65012 ADR65013 ADR65014 ADR65015 ADR65018 ADR65020 ADR65021 ADR65022 ADR65023 ADR65024 ADR65025 ADR65026 ADR65027 ADR65028 ADR65029 ADR65030 ADR65032 ADR65033 ADR65034 ADR65035 ADR65036 ADR65037 ADR65039 ADR65040 ADR65041 ADR65042 ADR65043 ADR65044 ADR65047 ADR65049 ADR65051 ADR65052 ADR65053 ADR65054 ADR65055 ADR65056 ADR65057 ADR65058 ADR65059 ADR65060 ADR65061 ADR65062 ADR65063 ADR65064 ADR65065 ADR65066 ADR65067 ADR65068 ADR65069 ADR65070 ADR65071 ADR65072 ADR65073 BAE79273 CAA63436 CAB41533 EAW65853
RNA Seq Atlas 5083

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca