Version 5.4
Homo sapiens Gene: CNDP1
Summary
InnateDB Gene IDBG-5062.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CNDP1
Gene Name carnosine dipeptidase 1 (metallopeptidase M20 family)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000150656
Encoded Proteins
IDBP-5064
carnosine dipeptidase 1 (metallopeptidase M20 family)
IDBP-726150
IDBP-725825
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:74534440-74587212
Strand Forward strand
Band q22.3
Transcripts
ENST00000358821 ENSP00000351682
ENST00000582365 ENSP00000462096
ENST00000582461
ENST00000584004
ENST00000585136
ENST00000578498
ENST00000584316 ENSP00000463807
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004180 carboxypeptidase activity
GO:0008237 metallopeptidase activity
GO:0016787 hydrolase activity
GO:0016805 dipeptidase activity
GO:0034701 tripeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0008152 metabolic process
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000056162
View Gene Order
ENSBTAG00000021428
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00340
Histidine metabolism pathway
hsa00330
Arginine and proline metabolism pathway
hsa00410
beta-Alanine metabolism pathway
INOH
INOH website
Histidine degradation pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.400613 Hs.631193 Hs.640886
RefSeq NM_032649
HUGO
OMIM
CCDS CCDS12007
HPRD 09894
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca