Version 5.4
Homo sapiens Gene: LGALS13
Summary
InnateDB Gene IDBG-50713.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LGALS13
Gene Name lectin, galactoside-binding, soluble, 13
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000105198
Encoded Proteins
IDBP-50715
lectin, galactoside-binding, soluble, 13
IDBP-763500
IDBP-809389
lectin, galactoside-binding, soluble, 13
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene has lysophospholipase activity. It is composed of two identical subunits which are held together by disulfide bonds. This protein has structural similarity to several members of the beta-galactoside-binding S-type lectin family. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:39602501-39607476
Strand Forward strand
Band q13.2
Transcripts
ENST00000221797 ENSP00000221797
ENST00000600546
ENST00000600141 ENSP00000470928
ENST00000621475 ENSP00000483444
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004622 lysophospholipase activity
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0006644 phospholipid metabolic process
GO:0006915 apoptotic process
Cellular Component
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_013268
HUGO
OMIM
CCDS CCDS33024
HPRD 16375
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca